Isopeptidases in anticancer therapy: looking for inhibitors

Por Sgorbissa, Andrea, Potu, Harish, Brancolini, Claudio
Publicado em 2010

The DeISGylase USP18 limits TRAIL-induced apoptosis through the regulation of TRAIL levels: Cellular levels of TRAIL influences responsiveness to TRAIL-induced apoptosis

Por Manini, Ivana, Sgorbissa, Andrea, Potu, Harish, Tomasella, Andrea, Brancolini, Claudio
Publicado em 2013

Tumor necrosis factor related apoptosis inducing ligand (TRAIL) regulates deubiquitinase USP5 in tumor cells

Por Potu, Harish, Kandarpa, Malathi, Peterson, Luke F., Donato, Nicholas J., Talpaz, Moshe
Publicado no Oncotarget (2019)

The Isopeptidase Inhibitor G5 Triggers a Caspase-independent Necrotic Death in Cells Resistant to Apoptosis: A COMPARATIVE STUDY WITH THE PROTEASOME INHIBITOR BORTEZOMIB

Por Fontanini, Alessandra, Foti, Carmela, Potu, Harish, Crivellato, Enrico, Maestro, Roberta, Bernardi, Paolo, Demarchi, Francesca, Brancolini, Claudio
Publicado em 2009

Usp5 links suppression of p53 and FAS levels in melanoma to the BRAF pathway

Por Potu, Harish, Peterson, Luke F., Pal, Anupama, Verhaegen, Monique, Cao, Juxiang, Talpaz, Moshe, Donato, Nicholas J.
Publicado em 2014

Usp9x Promotes Survival in Human Pancreatic Cancer and Its Inhibition Suppresses Pancreatic Ductal Adenocarcinoma In Vivo Tumor Growth()

Por Pal, Anupama, Dziubinski, Michele, Di Magliano, Marina Pasca, Simeone, Diane M., Owens, Scott, Thomas, Dafydd, Peterson, Luke, Potu, Harish, Talpaz, Moshe, Donato, Nicholas J.
Publicado no Neoplasia (2017)

Usp9x regulates Ets-1 ubiquitination and stability to control NRAS expression and tumorigenicity in melanoma

Por Potu, Harish, Peterson, Luke F., Kandarpa, Malathi, Pal, Anupama, Sun, Hanshi, Durham, Alison, Harms, Paul W., Hollenhorst, Peter C., Eskiocak, Ugur, Talpaz, Moshe, Donato, Nicholas J.
Publicado no Nat Commun (2017)