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Tumor necrosis factor related apoptosis inducing ligand (TRAIL) regulates deubiquitinase USP5 in tumor cells

The tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) pathway has emerged as a cancer therapeutic target. However, clinical trials have proven that most human cancers are resistant to TRAIL. We show that exposure to recombinant TRAIL resulted in the accumulation of ubiquitinated protei...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Potu, Harish, Kandarpa, Malathi, Peterson, Luke F., Donato, Nicholas J., Talpaz, Moshe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791380/
https://ncbi.nlm.nih.gov/pubmed/31645897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27196
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