TFF1 activates p53 through down-regulation of miR-504 in gastric cancer

The expression of TFF1 is frequently down-regulated in human gastric cancer whereas its knockout leads to the development of gastric adenomas and carcinomas in mouse models. The molecular mechanisms underlying the TFF1 tumor suppressor functions remain unclear. In this study, we demonstrate, using c...

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Hauptverfasser: Soutto, Mohammed, Chen, Zheng, Saleh, Mohamed A., Katsha, Ahmed, Zhu, Shoumin, Zaika, Alexander, Belkhiri, Abbes, El-Rifai, Wael
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2014
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170596/
https://ncbi.nlm.nih.gov/pubmed/25015107
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