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Activation of β-catenin Signaling by TFF1 Loss Promotes Cell Proliferation and Gastric Tumorigenesis
OBJECTIVE: In this study, we investigated the role of TFF1 in regulating cell proliferation and tumor development through β-catenin signaling using in vivo and in vitro models of gastric tumorigenesis. DESIGN: TFF1-Knockout mice, Immunohistochemistry, luciferase reporter, qRT-PCR, immunoblot and pho...
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Publicado no: | Gut |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4320984/ https://ncbi.nlm.nih.gov/pubmed/25107557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-307191 |
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