Activation of β-catenin Signaling by TFF1 Loss Promotes Cell Proliferation and Gastric Tumorigenesis

OBJECTIVE: In this study, we investigated the role of TFF1 in regulating cell proliferation and tumor development through β-catenin signaling using in vivo and in vitro models of gastric tumorigenesis. DESIGN: TFF1-Knockout mice, Immunohistochemistry, luciferase reporter, qRT-PCR, immunoblot and pho...

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Vydáno v:Gut
Hlavní autoři: Soutto, Mohammed, Peng, DunFa, Katsha, Ahmed, Chen, Zheng, Piazuelo, M. Blanca, Washington, M. Kay, Belkhiri, Abbes, Correa, Pelayo, El-Rifai, Wael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320984/
https://ncbi.nlm.nih.gov/pubmed/25107557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-307191
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