Loss of Tff1 Promotes Pro-Inflammatory Phenotype with Increase in the Levels of RORγt+ T Lymphocytes and Il-17 in Mouse Gastric Neoplasia

Background: TFF1 deficiency induces a mucosal pro-inflammatory phenotype that contributes to gastric tumorigenesis in mouse and human. Methods: We utilized the Tff1-KO mouse model to assess the impact of TFF1 loss on immune cells infiltration in the stomach. We used single cell suspension, flow cyto...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Soutto, Mohammed, Saleh, Mohamed, Arredouani, Mohamed S, Piazuelo, Blanca, Belkhiri, Abbes, El-Rifai, Wael
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595071/
https://ncbi.nlm.nih.gov/pubmed/28900479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.19639
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