TFF1 activates p53 through down-regulation of miR-504 in gastric cancer

The expression of TFF1 is frequently down-regulated in human gastric cancer whereas its knockout leads to the development of gastric adenomas and carcinomas in mouse models. The molecular mechanisms underlying the TFF1 tumor suppressor functions remain unclear. In this study, we demonstrate, using c...

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Autors principals: Soutto, Mohammed, Chen, Zheng, Saleh, Mohamed A., Katsha, Ahmed, Zhu, Shoumin, Zaika, Alexander, Belkhiri, Abbes, El-Rifai, Wael
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170596/
https://ncbi.nlm.nih.gov/pubmed/25015107
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