Evaluation of σ-1 Receptor Radioligand (18)F-FTC-146 in Rats and Squirrel Monkeys Using PET

The noninvasive imaging of σ-1 receptors (S1Rs) could provide insight into their role in different diseases and lead to novel diagnostic/treatment strategies. The main objective of this study was to assess the S1R radiotracer (18)F-FTC-146 in rats. Preliminary squirrel monkey imaging and human serum...

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Hauptverfasser: James, Michelle L., Shen, Bin, Nielsen, Carsten H., Behera, Deepak, Buckmaster, Christine L., Mesangeau, Christophe, Zavaleta, Cristina, Vuppala, Pradeep K., Jamalapuram, Seshulatha, Avery, Bonnie A., Lyons, David M., McCurdy, Christopher R., Biswal, Sandip, Gambhir, Sanjiv S., Chin, Frederick T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170105/
https://ncbi.nlm.nih.gov/pubmed/24337599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.113.120261
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