Aβ seeds resist inactivation by formaldehyde

Cerebral β-amyloidosis can be exogenously induced by the intracerebral injection of brain extracts containing aggregated β-amyloid (Aβ) into young, pre-depositing Aβ precursor protein- (APP) transgenic mice. Previous work has shown that the induction involves a prion-like seeding mechanism in which...

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Detalhes bibliográficos
Main Authors: Fritschi, Sarah K., Cintron, Amarallys, Ye, Lan, Mahler, Jasmin, Bühler, Anika, Baumann, Frank, Neumann, Manuela, Nilsson, K. Peter R., Hammarström, Per, Walker, Lary C., Jucker, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169116/
https://ncbi.nlm.nih.gov/pubmed/25193240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-014-1339-2
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