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Aβ seeds and prions: How close the fit?

The prion paradigm is increasingly invoked to explain the molecular pathogenesis of neurodegenerative diseases involving the misfolding and aggregation of proteins other than the prion protein (PrP). Extensive evidence from in vitro and in vivo studies indicates that misfolded and aggregated Aβ pept...

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Pubblicato in:Prion
Autori principali: Rasmussen, Jay, Jucker, Mathias, Walker, Lary C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553305/
https://ncbi.nlm.nih.gov/pubmed/28657440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2017.1334029
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