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Aβ seeds and prions: How close the fit?

The prion paradigm is increasingly invoked to explain the molecular pathogenesis of neurodegenerative diseases involving the misfolding and aggregation of proteins other than the prion protein (PrP). Extensive evidence from in vitro and in vivo studies indicates that misfolded and aggregated Aβ pept...

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Detalhes bibliográficos
Publicado no:Prion
Main Authors: Rasmussen, Jay, Jucker, Mathias, Walker, Lary C.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553305/
https://ncbi.nlm.nih.gov/pubmed/28657440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2017.1334029
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