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Substrate- and Cofactor-independent Inhibition of Histone Demethylase KDM4C
[Image: see text] Inhibition of histone demethylases has within recent years advanced into a new strategy for treating cancer and other diseases. Targeting specific histone demethylases can be challenging, as the active sites of KDM1A-B and KDM4A-D histone demethylases are highly conserved. Most inh...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4168794/ https://ncbi.nlm.nih.gov/pubmed/25014588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500374f |
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