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Treatment of glioblastoma multiforme using combination of siRNA targeting EGFR and β-catenin
BACKGROUND: EGFR and β-catenin are two key mediators of cell signal transduction implicated in the pathogenesis of a variety of tumors. There is emerging evidence indicating that they are overexpressed in glioblastoma multiforme (GBM) and both play significant roles in GBM carcinogenesis. Moreover,...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4167580/ https://ncbi.nlm.nih.gov/pubmed/23319157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.2693 |
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