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pH-sensitive siRNA Nanovector for Targeted Gene Silencing and Cytotoxic Effect in Cancer Cells

A small interfering RNA (siRNA) nanovector with dual targeting specificity and dual therapeutic effect is developed for targeted cancer imaging and therapy. The nanovector is comprised of an iron oxide magnetic nanoparticle core coated with three different functional molecules: polyethyleneimine (PE...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Mok, Hyejung, Veiseh, Omid, Fang, Chen, Kievit, Forrest M., Wang, Freddy Y., Park, James O., Zhang, Miqin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997854/
https://ncbi.nlm.nih.gov/pubmed/20722417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp100221h
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