pH-sensitive siRNA Nanovector for Targeted Gene Silencing and Cytotoxic Effect in Cancer Cells

A small interfering RNA (siRNA) nanovector with dual targeting specificity and dual therapeutic effect is developed for targeted cancer imaging and therapy. The nanovector is comprised of an iron oxide magnetic nanoparticle core coated with three different functional molecules: polyethyleneimine (PE...

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Bibliografiske detaljer
Main Authors: Mok, Hyejung, Veiseh, Omid, Fang, Chen, Kievit, Forrest M., Wang, Freddy Y., Park, James O., Zhang, Miqin
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997854/
https://ncbi.nlm.nih.gov/pubmed/20722417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp100221h
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