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pH-sensitive siRNA Nanovector for Targeted Gene Silencing and Cytotoxic Effect in Cancer Cells

A small interfering RNA (siRNA) nanovector with dual targeting specificity and dual therapeutic effect is developed for targeted cancer imaging and therapy. The nanovector is comprised of an iron oxide magnetic nanoparticle core coated with three different functional molecules: polyethyleneimine (PE...

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Библиографические подробности
Главные авторы: Mok, Hyejung, Veiseh, Omid, Fang, Chen, Kievit, Forrest M., Wang, Freddy Y., Park, James O., Zhang, Miqin
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997854/
https://ncbi.nlm.nih.gov/pubmed/20722417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp100221h
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