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Cell transcytosing poly-arginine coated magnetic nanovector for safe and effective siRNA delivery
Lack of safe and effective carriers for delivery of RNA therapeutics remains a barrier to its broad clinical application. We report the development of a cell tanscytosing magnetic nanovector engineered as an siRNA carrier. Iron oxide nanoparticles were modified with poly(ethylene glycol) (PEG), smal...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3125526/ https://ncbi.nlm.nih.gov/pubmed/21570721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.04.039 |
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