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Cell transcytosing poly-arginine coated magnetic nanovector for safe and effective siRNA delivery

Lack of safe and effective carriers for delivery of RNA therapeutics remains a barrier to its broad clinical application. We report the development of a cell tanscytosing magnetic nanovector engineered as an siRNA carrier. Iron oxide nanoparticles were modified with poly(ethylene glycol) (PEG), smal...

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Detalhes bibliográficos
Main Authors: Veiseh, Omid, Kievit, Forrest M., Mok, Hyejung, Ayesh, Joseph, Clark, Cassra, Fang, Chen, Leung, Matthew, Arami, Hamed, Park, James O., Zhang, Miqin
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125526/
https://ncbi.nlm.nih.gov/pubmed/21570721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.04.039
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