RNA nanoparticle as a vector for targeted siRNA delivery into glioblastoma mouse model

Systemic siRNA administration to target and treat glioblastoma, one of the most deadly cancers, requires robust and efficient delivery platform without immunogenicity. Here we report newly emerged multivalent naked RNA nanoparticle (RNP) based on pRNA 3-way-junction (3WJ) from bacteriophage phi29 to...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Lee, Tae Jin, Haque, Farzin, Shu, Dan, Yoo, Ji Young, Li, Hui, Yokel, Robert A., Horbinski, Craig, Kim, Tae Hyong, Kim, Sung-Hak, Kwon, Chang-Hyuk, Nakano, Ichiro, Kaur, Balveen, Guo, Peixuan, Croce, Carlo M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2015
Konular:
Priority Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558114/
https://ncbi.nlm.nih.gov/pubmed/25885522
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