RNA nanoparticle as a vector for targeted siRNA delivery into glioblastoma mouse model

Systemic siRNA administration to target and treat glioblastoma, one of the most deadly cancers, requires robust and efficient delivery platform without immunogenicity. Here we report newly emerged multivalent naked RNA nanoparticle (RNP) based on pRNA 3-way-junction (3WJ) from bacteriophage phi29 to...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Lee, Tae Jin, Haque, Farzin, Shu, Dan, Yoo, Ji Young, Li, Hui, Yokel, Robert A., Horbinski, Craig, Kim, Tae Hyong, Kim, Sung-Hak, Kwon, Chang-Hyuk, Nakano, Ichiro, Kaur, Balveen, Guo, Peixuan, Croce, Carlo M.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Priority Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558114/
https://ncbi.nlm.nih.gov/pubmed/25885522
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