RNA nanoparticle as a vector for targeted siRNA delivery into glioblastoma mouse model

Systemic siRNA administration to target and treat glioblastoma, one of the most deadly cancers, requires robust and efficient delivery platform without immunogenicity. Here we report newly emerged multivalent naked RNA nanoparticle (RNP) based on pRNA 3-way-junction (3WJ) from bacteriophage phi29 to...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Lee, Tae Jin, Haque, Farzin, Shu, Dan, Yoo, Ji Young, Li, Hui, Yokel, Robert A., Horbinski, Craig, Kim, Tae Hyong, Kim, Sung-Hak, Kwon, Chang-Hyuk, Nakano, Ichiro, Kaur, Balveen, Guo, Peixuan, Croce, Carlo M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Priority Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558114/
https://ncbi.nlm.nih.gov/pubmed/25885522
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge