RNA nanoparticle as a vector for targeted siRNA delivery into glioblastoma mouse model

Systemic siRNA administration to target and treat glioblastoma, one of the most deadly cancers, requires robust and efficient delivery platform without immunogenicity. Here we report newly emerged multivalent naked RNA nanoparticle (RNP) based on pRNA 3-way-junction (3WJ) from bacteriophage phi29 to...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lee, Tae Jin, Haque, Farzin, Shu, Dan, Yoo, Ji Young, Li, Hui, Yokel, Robert A., Horbinski, Craig, Kim, Tae Hyong, Kim, Sung-Hak, Kwon, Chang-Hyuk, Nakano, Ichiro, Kaur, Balveen, Guo, Peixuan, Croce, Carlo M.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Priority Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558114/
https://ncbi.nlm.nih.gov/pubmed/25885522
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