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Systemic influences contribute to prolonged microvascular rarefaction after brain irradiation: a role for endothelial progenitor cells
Whole brain radiation therapy (WBRT) induces profound cerebral microvascular rarefaction throughout the hippocampus. Despite the vascular loss and localized cerebral hypoxia, angiogenesis fails to occur, which subsequently induces long-term deficits in learning and memory. The mechanisms underlying...
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Main Authors: | , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
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American Physiological Society
2014
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4166745/ https://ncbi.nlm.nih.gov/pubmed/25038144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00308.2014 |
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