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MurJ is the flippase of lipid-linked precursors for peptidoglycan biogenesis
Peptidoglycan (PG) is a polysaccharide matrix that protects bacteria from osmotic lysis. Inhibition of its biogenesis is a proven strategy for killing bacteria with antibiotics. The assembly of PG requires disaccharide-pentapeptide building blocks attached to a polyisoprene lipid carrier called lipi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4163187/ https://ncbi.nlm.nih.gov/pubmed/25013077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1254522 |
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