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Structure and mutagenic analysis of the lipid II flippase MurJ from Escherichia coli

The peptidoglycan cell wall provides an essential protective barrier in almost all bacteria, defining cellular morphology and conferring resistance to osmotic stress and other environmental hazards. The precursor to peptidoglycan, lipid II, is assembled on the inner leaflet of the plasma membrane. H...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zheng, Sanduo, Sham, Lok-To, Rubino, Frederick A., Brock, Kelly P., Robins, William P., Mekalanos, John J., Marks, Debora S., Bernhardt, Thomas G., Kruse, Andrew C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042122/
https://ncbi.nlm.nih.gov/pubmed/29891673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802192115
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