Characterization of Mutants Deficient in the l,d-Carboxypeptidase (DacB) and WalRK (VicRK) Regulon, Involved in Peptidoglycan Maturation of Streptococcus pneumoniae Serotype 2 Stra...

由 Barendt, Skye M., Sham, Lok-To, Winkler, Malcolm E.
出版 2011

Kinetic Characterization of the WalRK(Spn) (VicRK) Two-Component System of Streptococcus pneumoniae: Dependence of WalK(Spn) (VicK) Phosphatase Activity on Its PAS Domain

由 Gutu, Alina D., Wayne, Kyle J., Sham, Lok-To, Winkler, Malcolm E.
出版 2010

Essential PcsB putative peptidoglycan hydrolase interacts with the essential FtsX(Spn) cell division protein in Streptococcus pneumoniae D39

由 Sham, Lok-To, Barendt, Skye M., Kopecky, Kimberly E., Winkler, Malcolm E.
出版 2011

Involvement of FtsE ATPase and FtsX Extracellular Loops 1 and 2 in FtsEX-PcsB Complex Function in Cell Division of Streptococcus pneumoniae D39

由 Sham, Lok-To, Jensen, Katelyn R., Bruce, Kevin E., Winkler, Malcolm E.
出版 2013

Loss of specificity variants of WzxC suggest that substrate recognition is coupled with transporter opening in MOP-family flippases

由 Sham, Lok To, Zheng, Sanduo, Yakhnina, Anastasiya A., Kruse, Andrew C., Bernhardt, Thomas G.
發表在 Mol Microbiol (2018)

Recent Advances in Pneumococcal Peptidoglycan Biosynthesis Suggest New Vaccine and Antimicrobial Targets

由 Sham, Lok-To, Tsui, Ho-Ching T., Land, Adrian D., Barendt, Skye M., Winkler, Malcolm E.
出版 2012

Cell envelope defects of different capsule‐null mutants in K1 hypervirulent Klebsiella pneumoniae can affect bacterial pathogenesis

由 Tan, Yi Han, Chen, Yahua, Chu, Wilson H. W., Sham, Lok‐To, Gan, Yunn‐Hwen
發表在 Mol Microbiol (2020)

Dynamic Distribution of the SecA and SecY Translocase Subunits and Septal Localization of the HtrA Surface Chaperone/Protease during Streptococcus pneumoniae D39 Cell Division

由 Tsui, Ho-Ching Tiffany, Keen, Susan K., Sham, Lok-To, Wayne, Kyle J., Winkler, Malcolm E.
出版 2011

FtsEX is required for CwlO peptidoglycan hydrolase activity during cell wall elongation in Bacillus subtilis

由 Meisner, Jeffrey, Llopis, Paula Montero, Sham, Lok-To, Garner, Ethan, Bernhardt, Thomas G., Rudner, David Z.
出版 2013

MurJ is the flippase of lipid-linked precursors for peptidoglycan biogenesis

由 Sham, Lok-To, Butler, Emily K., Lebar, Matthew D., Kahne, Daniel, Bernhardt, Thomas G., Ruiz, Natividad
出版 2014

RNA thermosensors facilitate Streptococcus pneumoniae and Haemophilus influenzae immune evasion

由 Eichner, Hannes, Karlsson, Jens, Spelmink, Laura, Pathak, Anuj, Sham, Lok-To, Henriques-Normark, Birgitta, Loh, Edmund
發表在 PLoS Pathog (2021)

Identification and Characterization of Noncoding Small RNAs in Streptococcus pneumoniae Serotype 2 Strain D39

由 Tsui, Ho-Ching Tiffany, Mukherjee, Dhriti, Ray, Valerie A., Sham, Lok-To, Feig, Andrew L., Winkler, Malcolm E.
出版 2010

Mechanistic Study of Utilization of Water-Insoluble Saccharomyces cerevisiae Glucans by Bifidobacterium breve Strain JCM1192

由 Keung, Hoi Yee, Li, Tsz Kai, Sham, Lok To, Cheung, Man Kit, Cheung, Peter Chi Keung, Kwan, Hoi Shan
發表在 Appl Environ Microbiol (2017)

MurJ and a novel lipid II flippase are required for cell wall biogenesis in Bacillus subtilis

由 Meeske, Alexander J., Sham, Lok-To, Kimsey, Harvey, Koo, Byoung-Mo, Gross, Carol A., Bernhardt, Thomas G., Rudner, David Z.
發表在 Proc Natl Acad Sci U S A (2015)

A viral protein antibiotic inhibits lipid II flippase activity

由 Chamakura, Karthik R., Sham, Lok-To, Davis, Rebecca M., Min, Lorna, Cho, Hongbaek, Ruiz, Natividad, Bernhardt, Thomas G., Young, Ry
發表在 Nat Microbiol (2017)

Influences of Capsule on Cell Shape and Chain Formation of Wild-Type and pcsB Mutants of Serotype 2 Streptococcus pneumoniae

由 Barendt, Skye M., Land, Adrian D., Sham, Lok-To, Ng, Wai-Leung, Tsui, Ho-Ching T., Arnold, Randy J., Winkler, Malcolm E.
出版 2009

Localization and Cellular Amounts of the WalRKJ (VicRKX) Two-Component Regulatory System Proteins in Serotype 2 Streptococcus pneumoniae

由 Wayne, Kyle J., Sham, Lok-To, Tsui, Ho-Ching T., Gutu, Alina D., Barendt, Skye M., Keen, Susan K., Winkler, Malcolm E.
出版 2010

DegU-phosphate activates expression of the anti-sigma factor FlgM in Bacillus subtilis

由 Hsueh, Yi-Huang, Cozy, Loralyn M., Sham, Lok-To, Calvo, Rebecca A., Gutu, Alina D., Winkler, Malcolm E., Kearns, Daniel B.
出版 2011

Selective Penicillin-Binding Protein Imaging Probes Reveal Substructure in Bacterial Cell Division

由 Kocaoglu, Ozden, Calvo, Rebecca A., Sham, Lok-To, Cozy, Loralyn M., Lanning, Bryan R., Francis, Samson, Winkler, Malcolm E., Kearns, Daniel B., Carlson, Erin E.
出版 2012

Structure and mutagenic analysis of the lipid II flippase MurJ from Escherichia coli

由 Zheng, Sanduo, Sham, Lok-To, Rubino, Frederick A., Brock, Kelly P., Robins, William P., Mekalanos, John J., Marks, Debora S., Bernhardt, Thomas G., Kruse, Andrew C.
發表在 Proc Natl Acad Sci U S A (2018)