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The bacterial lipid II flippase MurJ functions by an alternating-access mechanism

The peptidoglycan (PG) cell wall is an essential extracytoplasmic glycopeptide polymer that safeguards bacteria against osmotic lysis and determines cellular morphology. Bacteria use multiprotein machineries for the synthesis of the PG cell wall during cell division and elongation that can be target...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Kumar, Sujeet, Rubino, Frederick A., Mendoza, Alicia G., Ruiz, Natividad
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341377/
https://ncbi.nlm.nih.gov/pubmed/30482840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006099
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