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The bacterial lipid II flippase MurJ functions by an alternating-access mechanism

The peptidoglycan (PG) cell wall is an essential extracytoplasmic glycopeptide polymer that safeguards bacteria against osmotic lysis and determines cellular morphology. Bacteria use multiprotein machineries for the synthesis of the PG cell wall during cell division and elongation that can be target...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Kumar, Sujeet, Rubino, Frederick A., Mendoza, Alicia G., Ruiz, Natividad
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341377/
https://ncbi.nlm.nih.gov/pubmed/30482840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006099
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