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The bacterial lipid II flippase MurJ functions by an alternating-access mechanism

The peptidoglycan (PG) cell wall is an essential extracytoplasmic glycopeptide polymer that safeguards bacteria against osmotic lysis and determines cellular morphology. Bacteria use multiprotein machineries for the synthesis of the PG cell wall during cell division and elongation that can be target...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kumar, Sujeet, Rubino, Frederick A., Mendoza, Alicia G., Ruiz, Natividad
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341377/
https://ncbi.nlm.nih.gov/pubmed/30482840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006099
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