The Second Sodium Site in the Dopamine Transporter Controls Cation Permeation and Is Regulated by Chloride

The dopamine transporter (DAT) belongs to the family of neurotransmitter:sodium symporters and controls dopamine (DA) homeostasis by mediating Na(+)- and Cl(−)-dependent reuptake of DA. Here we used two-electrode voltage clamp measurements in Xenopus oocytes together with targeted mutagenesis to inv...

Full description

Saved in:
Bibliographic Details
Main Authors: Borre, Lars, Andreassen, Thorvald F., Shi, Lei, Weinstein, Harel, Gether, Ulrik
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Neurobiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162178/
https://ncbi.nlm.nih.gov/pubmed/25063810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.574269
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items