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The Second Sodium Site in the Dopamine Transporter Controls Cation Permeation and Is Regulated by Chloride
The dopamine transporter (DAT) belongs to the family of neurotransmitter:sodium symporters and controls dopamine (DA) homeostasis by mediating Na(+)- and Cl(−)-dependent reuptake of DA. Here we used two-electrode voltage clamp measurements in Xenopus oocytes together with targeted mutagenesis to inv...
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| Main Authors: | , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
American Society for Biochemistry and Molecular Biology
2014
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4162178/ https://ncbi.nlm.nih.gov/pubmed/25063810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.574269 |
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