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Heat shock protein 90 inhibitors in the treatment of cancer: current status and future directions
INTRODUCTION: Heat shock protein 90 (HSP90) serves as a critical facilitator for oncogene addiction. There has been augmenting enthusiasm in pursuing HSP90 as an anticancer strategy. In fact, since the initial serendipitous discovery that geldanamycin (GM) inhibits HSP90, the field has rapidly moved...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4161020/ https://ncbi.nlm.nih.gov/pubmed/24669860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543784.2014.902442 |
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