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CD4(+) T Lymphocyte Ablation Prevents Pancreatic Carcinogenesis in Mice

Pancreatic cancer, one of the deadliest human malignancies, is associated with oncogenic Kras and is most commonly preceded by precursor lesions known as pancreatic intraepithelial neoplasias (PanIN). PanIN formation is accompanied by the establishment of an immunotolerant microenvironment. However,...

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書誌詳細
主要な著者: Zhang, Yaqing, Yan, Wei, Mathew, Esha, Bednar, Filip, Wan, Shanshan, Collins, Meredith A., Evans, Rebecca A., Welling, Theodore H., Vonderheide, Robert H., di Magliano, Marina Pasca
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160804/
https://ncbi.nlm.nih.gov/pubmed/24795355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0016-T
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