CD4(+) T Lymphocyte Ablation Prevents Pancreatic Carcinogenesis in Mice

Pancreatic cancer, one of the deadliest human malignancies, is associated with oncogenic Kras and is most commonly preceded by precursor lesions known as pancreatic intraepithelial neoplasias (PanIN). PanIN formation is accompanied by the establishment of an immunotolerant microenvironment. However,...

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Bibliographic Details
Main Authors:	Zhang, Yaqing, Yan, Wei, Mathew, Esha, Bednar, Filip, Wan, Shanshan, Collins, Meredith A., Evans, Rebecca A., Welling, Theodore H., Vonderheide, Robert H., di Magliano, Marina Pasca
Format:	Artigo
Language:	Inglês
Published:	2014
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4160804/ https://ncbi.nlm.nih.gov/pubmed/24795355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0016-T
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CD4(+) T Lymphocyte Ablation Prevents Pancreatic Carcinogenesis in Mice

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