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CD4(+) T Lymphocyte Ablation Prevents Pancreatic Carcinogenesis in Mice

Pancreatic cancer, one of the deadliest human malignancies, is associated with oncogenic Kras and is most commonly preceded by precursor lesions known as pancreatic intraepithelial neoplasias (PanIN). PanIN formation is accompanied by the establishment of an immunotolerant microenvironment. However,...

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Detalhes bibliográficos
Main Authors: Zhang, Yaqing, Yan, Wei, Mathew, Esha, Bednar, Filip, Wan, Shanshan, Collins, Meredith A., Evans, Rebecca A., Welling, Theodore H., Vonderheide, Robert H., di Magliano, Marina Pasca
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160804/
https://ncbi.nlm.nih.gov/pubmed/24795355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0016-T
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