CD4(+) T Lymphocyte Ablation Prevents Pancreatic Carcinogenesis in Mice

Pancreatic cancer, one of the deadliest human malignancies, is associated with oncogenic Kras and is most commonly preceded by precursor lesions known as pancreatic intraepithelial neoplasias (PanIN). PanIN formation is accompanied by the establishment of an immunotolerant microenvironment. However,...

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Main Authors: Zhang, Yaqing, Yan, Wei, Mathew, Esha, Bednar, Filip, Wan, Shanshan, Collins, Meredith A., Evans, Rebecca A., Welling, Theodore H., Vonderheide, Robert H., di Magliano, Marina Pasca
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160804/
https://ncbi.nlm.nih.gov/pubmed/24795355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0016-T
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