Glucose induces intestinal human UDP-glucuronosyltransferase (UGT) 1A1 to prevent neonatal hyperbilirubinemia

Inadequate calorie intake or starvation has been suggested as a cause of neonatal jaundice, which can further cause permanent brain damage, kernicterus. This study experimentally investigated whether additional glucose treatments induce the bilirubin-metabolizing enzyme – UDP-glucuronosyltransferase...

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Main Authors: Aoshima, Naoya, Fujie, Yoshiko, Itoh, Tomoo, Tukey, Robert H., Fujiwara, Ryoichi
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160704/
https://ncbi.nlm.nih.gov/pubmed/25209391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06343
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