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BACE1 (β-Secretase) Inhibitors for the Treatment of Alzheimer's Disease

BACE1 (β-secretase, memapsin 2, Asp2) has emerged as a promising target for the treatment of Alzheimer's Disease. BACE1 is an aspartic protease which functions in the first step of the pathway leading to the production and deposition of amyloid-β peptide (Aβ). Its gene deletion showed only mild...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Ghosh, Arun K., Osswald, Heather L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159447/
https://ncbi.nlm.nih.gov/pubmed/24691405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cs60460h
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