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BACE1 (β-Secretase) Inhibitors for the Treatment of Alzheimer's Disease
BACE1 (β-secretase, memapsin 2, Asp2) has emerged as a promising target for the treatment of Alzheimer's Disease. BACE1 is an aspartic protease which functions in the first step of the pathway leading to the production and deposition of amyloid-β peptide (Aβ). Its gene deletion showed only mild...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4159447/ https://ncbi.nlm.nih.gov/pubmed/24691405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cs60460h |
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