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Prospects of β-Secretase Inhibitors for the Treatment of Alzheimer’s Disease

β-Secretase continues to be an attractive drug discovery target for the therapeutic intervention of Alzheimer’s disease (AD). This enzyme plays a critical role in the production of neurotoxic β-amyloid (Aβ) peptides in the brain. Over the years, extensive research efforts have led to the development...

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Detalhes bibliográficos
Publicado no:ChemMedChem
Main Authors: Ghosh, Arun K., Tang, Jordan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6029879/
https://ncbi.nlm.nih.gov/pubmed/26140607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201500216
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