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Error-prone polymerase activity causes multinucleotide mutations in humans

About 2% of human genetic polymorphisms have been hypothesized to arise via multinucleotide mutations (MNMs), complex events that generate SNPs at multiple sites in a single generation. MNMs have the potential to accelerate the pace at which single genes evolve and to confound studies of demography...

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Detaylı Bibliyografya
Asıl Yazarlar: Harris, Kelley, Nielsen, Rasmus
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158752/
https://ncbi.nlm.nih.gov/pubmed/25079859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.170696.113
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