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Error-prone polymerase activity causes multinucleotide mutations in humans
About 2% of human genetic polymorphisms have been hypothesized to arise via multinucleotide mutations (MNMs), complex events that generate SNPs at multiple sites in a single generation. MNMs have the potential to accelerate the pace at which single genes evolve and to confound studies of demography...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4158752/ https://ncbi.nlm.nih.gov/pubmed/25079859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.170696.113 |
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