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Error-prone lesion bypass by human DNA polymerase η

DNA lesion bypass is an important cellular response to genomic damage during replication. Human DNA polymerase η (Polη), encoded by the Xeroderma pigmentosum variant (XPV) gene, is known for its activity of error-free translesion synthesis opposite a TT cis-syn cyclobutane dimer. Using purified huma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Yanbin, Yuan, Fenghua, Wu, Xiaohua, Rechkoblit, Olga, Taylor, John-Stephen, Geacintov, Nicholas E., Wang, Zhigang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC115171/
https://ncbi.nlm.nih.gov/pubmed/11095682
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