Clonal Evolution in Breast Cancer Revealed by Single Nucleus Genome Sequencing

Sequencing studies of breast tumor cohorts have identified many prevalent mutations, but provide limited insight into the genomic diversity within tumors. Here, we developed a whole-genome and exome single cell sequencing approach called Nuc-Seq that utilizes G2/M nuclei to achieve 91% mean coverage...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Wang, Yong, Waters, Jill, Leung, Marco L., Unruh, Anna, Roh, Whijae, Shi, Xiuqing, Chen, Ken, Scheet, Paul, Vattathil, Selina, Liang, Han, Multani, Asha, Zhang, Hong, Zhao, Rui, Michor, Franziska, Meric-Bernstam, Funda, Navin, Nicholas E.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158312/
https://ncbi.nlm.nih.gov/pubmed/25079324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13600
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker