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Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells
Pluripotent stem cells exist in naive and primed states, epitomized by mouse embryonic stem cells (ESCs) and the developmentally more advanced epiblast stem cells (EpiSCs; ref. 1). In the naive state of ESCs, the genome has an unusual open conformation and possesses a minimum of repressive epigeneti...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4157727/ https://ncbi.nlm.nih.gov/pubmed/21841791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2314 |
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