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Wnt signaling mediates self-organization and axis formation in embryoid bodies

Embryonic stem cells form descendants of all three germ layers when differentiated as aggregates, termed embryoid bodies. In vivo, differentiation of cells depends on signals and morphogen gradients that provide instructive and positional cues, but do such gradients exist in embryoid bodies? We repo...

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Bibliografiske detaljer
Main Authors: Berge, Derk ten, Koole, Wouter, Fuerer, Christophe, Fish, Matt, Eroglu, Elif, Nusse, Roel
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683270/
https://ncbi.nlm.nih.gov/pubmed/18983966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2008.09.013
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