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A study on the interactions between Heparan Sulfate Proteoglycans and Wnt proteins

The Wnt signaling pathway plays key roles in development and adult homeostasis. Wnt proteins are secreted, lipid-modified glycoproteins. They can form morphogen gradients that are regulated at the level of protein secretion, diffusion, and internalization. These gradients can only exist if the hydro...

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Autores principales: Fuerer, Christophe, Habib, Shukry J., Nusse, Roel
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846786/
https://ncbi.nlm.nih.gov/pubmed/19705435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22067
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