Characterization of a monoclonal antibody to a novel glycan-dependent epitope in the V1/V2 domain of the HIV-1 envelope protein, gp120

Recent studies have described several broadly neutralizing monoclonal antibodies (bN-mAbs) that recognize glycan-dependent epitopes (GDEs) in the HIV-1 envelope protein, gp120. These were recovered from HIV-1 infected subjects, and several (e.g., PG9, PG16, CH01, CH03) target glycans in the first an...

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Autors principals: Doran, Rachel C., Morales, Javier F., To, Briana, Morin, Trevor J., Theolis Jr., Richard, O’Rourke, Sara M., Yu, Bin, Mesa, Kathryn A., Berman, Phillip W.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Ltd. 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157072/
https://ncbi.nlm.nih.gov/pubmed/25016576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2014.06.025
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