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Proximal glycans outside of the epitopes regulate the presentation of HIV-1 envelope gp120 helper epitopes

Glycosylation of HIV-1 envelope gp120 determines not only the proper structure, but also the immune responses against this antigen. While glycans may be part of specific epitopes or shield other epitopes from T cells and antibodies, this study provides evidence for a different immunomodulatory funct...

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Autors principals: Li, Hualin, Xu, Chong-Feng, Blais, Steven, Wan, Qi, Zhang, Hui-Tang, Landry, Samuel J., Hioe, Catarina E.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808118/
https://ncbi.nlm.nih.gov/pubmed/19414790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0804287
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