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Antigen structure influences helper T-cell epitope dominance in the human immune response to HIV envelope glycoprotein gp120
The development of an effective vaccine against HIV/AIDS has been hampered, in part, by a poor understanding of the rules governing helper T-cell epitope immunodominance. Studies in mice have shown that antigen structure modulates epitope immunodominance by affecting the processing and subsequent pr...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3855344/ https://ncbi.nlm.nih.gov/pubmed/18398933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200738011 |
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