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Improving immunogenicity of HIV-1 envelope gp120 by glycan removal and immune complex formation
HIV-1 envelope (Env) gp120 is an important target for neutralizing antibody (Ab) responses against the virus; however, developing gp120 vaccines that elicit potent and broad neutralizing Abs has proven to be a formidable challenge. Previously, removal of an N-linked glycan at residue 448 by an N to...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3328143/ https://ncbi.nlm.nih.gov/pubmed/21945958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.09.057 |
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