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In vivo alteration of humoral responses to HIV-1 envelope glycoprotein gp120 by antibodies to the CD4-binding site of gp120

The binding of antibodies to the CD4-binding site (CD4bs) of the HIV-1 envelope glycoprotein gp120 has been shown to induce gp120 to undergo conformational changes that can expose and/or shield specific epitopes on gp120. Here, we study alterations in the antigenicity and immunogenicity of gp120 whe...

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Bibliografske podrobnosti
Main Authors: Visciano, Maria Luisa, Tuen, Michael, Gorny, Miroslaw K., Hioe, Catarina E.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2288784/
https://ncbi.nlm.nih.gov/pubmed/18054978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.10.044
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