تحميل...
Bioenergetic modulation with dichloroacetate reduces the growth of melanoma cells and potentiates their response to BRAF(V600E) inhibition
BACKGROUND: Advances in melanoma treatment through targeted inhibition of oncogenic BRAF are limited owing to the development of acquired resistance. The involvement of BRAF(V600E) in metabolic reprogramming of melanoma cells provides a rationale for co-targeting metabolism as a therapeutic approach...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , |
|---|---|
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
BioMed Central
2014
|
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4156963/ https://ncbi.nlm.nih.gov/pubmed/25182332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-014-0247-5 |
| الوسوم: |
إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!
|