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Multiple Functions for Mcm2-7 ATPase Motifs During Replication Initiation

The Mcm2-7 replicative helicase is central to all steps of eukaryotic DNA replication. The hexameric ring of Mcm subunits forms six essential ATPases whose contributions to replication initiation remain unclear. Mcm2-7 complexes containing ATPase-motif mutations showed Mcm2-7 ATP binding and hydroly...

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Bibliografische gegevens
Hoofdauteurs: Kang, Sukhyun, Warner, Megan D., Bell, Stephen P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156824/
https://ncbi.nlm.nih.gov/pubmed/25087876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.06.033
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