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Multiple Functions for Mcm2-7 ATPase Motifs During Replication Initiation
The Mcm2-7 replicative helicase is central to all steps of eukaryotic DNA replication. The hexameric ring of Mcm subunits forms six essential ATPases whose contributions to replication initiation remain unclear. Mcm2-7 complexes containing ATPase-motif mutations showed Mcm2-7 ATP binding and hydroly...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4156824/ https://ncbi.nlm.nih.gov/pubmed/25087876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.06.033 |
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