Nucleosomes influence multiple steps during replication initiation

Eukaryotic replication origin licensing, activation and timing are influenced by chromatin but a mechanistic understanding is lacking. Using reconstituted nucleosomal DNA replication assays, we assessed the impact of nucleosomes on replication initiation. To generate distinct nucleosomal landscapes,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Azmi, Ishara F, Watanabe, Shinya, Maloney, Michael F, Kang, Sukhyun, Belsky, Jason A, MacAlpine, David M, Peterson, Craig L, Bell, Stephen P
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2017
Pynciau:
Biochemistry
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400510/
https://ncbi.nlm.nih.gov/pubmed/28322723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.22512
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