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Genome-wide chromatin footprinting reveals changes in replication origin architecture induced by pre-RC assembly

Start sites of DNA replication are marked by the origin recognition complex (ORC), which coordinates Mcm2–7 helicase loading to form the prereplicative complex (pre-RC). Although pre-RC assembly is well characterized in vitro, the process is poorly understood within the local chromatin environment s...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Belsky, Jason A., MacAlpine, Heather K., Lubelsky, Yoav, Hartemink, Alexander J., MacAlpine, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298139/
https://ncbi.nlm.nih.gov/pubmed/25593310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.247924.114
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