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Multiple Functions for Mcm2-7 ATPase Motifs During Replication Initiation
The Mcm2-7 replicative helicase is central to all steps of eukaryotic DNA replication. The hexameric ring of Mcm subunits forms six essential ATPases whose contributions to replication initiation remain unclear. Mcm2-7 complexes containing ATPase-motif mutations showed Mcm2-7 ATP binding and hydroly...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4156824/ https://ncbi.nlm.nih.gov/pubmed/25087876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.06.033 |
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