Functional Analysis of Dishevelled-3 Phosphorylation Identifies Distinct Mechanisms Driven by Casein Kinase 1ϵ and Frizzled5

Dishevelled-3 (Dvl3), a key component of the Wnt signaling pathways, acts downstream of Frizzled (Fzd) receptors and gets heavily phosphorylated in response to pathway activation by Wnt ligands. Casein kinase 1ϵ (CK1ϵ) was identified as the major kinase responsible for Wnt-induced Dvl3 phosphorylati...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Bernatík, Ondřej, Šedová, Kateřina, Schille, Carolin, Ganji, Ranjani Sri, Červenka, Igor, Trantírek, Lukáš, Schambony, Alexandra, Zdráhal, Zbyněk, Bryja, Vítězslav
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156093/
https://ncbi.nlm.nih.gov/pubmed/24993822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.590638
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados