Sequential Activation and Inactivation of Dishevelled in the Wnt/β-Catenin Pathway by Casein Kinases

Dishevelled (Dvl) is a key component in the Wnt/β-catenin signaling pathway. Dvl can multimerize to form dynamic protein aggregates, which are required for the activation of downstream signaling. Upon pathway activation by Wnts, Dvl becomes phosphorylated to yield phosphorylated and shifted (PS) Dvl...

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מידע ביבליוגרפי
Main Authors: Bernatik, Ondrej, Ganji, Ranjani Sri, Dijksterhuis, Jacomijn P., Konik, Peter, Cervenka, Igor, Polonio, Tilman, Krejci, Pavel, Schulte, Gunnar, Bryja, Vitezslav
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2011
נושאים:
Cell Biology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060493/
https://ncbi.nlm.nih.gov/pubmed/21285348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.169870
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