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Dishevelled enables casein kinase 1–mediated phosphorylation of Frizzled 6 required for cell membrane localization
Frizzleds (FZDs) are receptors for secreted lipoglycoproteins of the Wingless/Int-1 (WNT) family, initiating an important signal transduction network in multicellular organisms. FZDs are G protein–coupled receptors (GPCRs), which are well known to be regulated by phosphorylation, leading to specific...
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| 發表在: | J Biol Chem |
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| Main Authors: | , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6290145/ https://ncbi.nlm.nih.gov/pubmed/30309985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004656 |
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