Dishevelled enables casein kinase 1–mediated phosphorylation of Frizzled 6 required for cell membrane localization

Frizzleds (FZDs) are receptors for secreted lipoglycoproteins of the Wingless/Int-1 (WNT) family, initiating an important signal transduction network in multicellular organisms. FZDs are G protein–coupled receptors (GPCRs), which are well known to be regulated by phosphorylation, leading to specific...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Strakova, Katerina, Kowalski-Jahn, Maria, Gybel, Tomas, Valnohova, Jana, Dhople, Vishnu M., Harnos, Jakub, Bernatik, Ondrej, Ganji, Ranjani Sri, Zdrahal, Zbynek, Mulder, Jan, Lindskog, Cecilia, Bryja, Vitezslav, Schulte, Gunnar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290145/
https://ncbi.nlm.nih.gov/pubmed/30309985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004656
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