Efficacy of Cidofovir in a Murine Model of Disseminated Progressive Vaccinia

An animal model that mimics progressive disseminated vaccinia was elaborated. To this end nude (athymic) mice were inoculated intracutaneously with vaccinia virus in the lumbosacral area. Viral replication (DNA) in the skin was detected as early as day 2 postinfection (p.i.). Mice developed typical...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Neyts, Johan, Leyssen, Pieter, Verbeken, Erik, De Clercq, Erik
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2004
Assuntos:
Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC415602/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15155231/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.6.2267-2273.2004
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