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Efficacy of Cidofovir in a Murine Model of Disseminated Progressive Vaccinia

An animal model that mimics progressive disseminated vaccinia was elaborated. To this end nude (athymic) mice were inoculated intracutaneously with vaccinia virus in the lumbosacral area. Viral replication (DNA) in the skin was detected as early as day 2 postinfection (p.i.). Mice developed typical...

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Autori principali: Neyts, Johan, Leyssen, Pieter, Verbeken, Erik, De Clercq, Erik
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC415602/
https://ncbi.nlm.nih.gov/pubmed/15155231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.6.2267-2273.2004
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